DNA binding proteins

Complexes of Cytosolic Proteins

In collaboration with Wolf Heyer and Steve Kowalczykowski, UC Davis, we also study DNA binding proteins responsible for chromosome maintenance and repair. In collaboration with Roland Riek, ETH Zürich, Switzerland, we study prion proteins. We also collaborate with Susan Gasser, FMI, and Nicola Thomae, FMI, on the structure of DNA binding protein complexes that are involved in silencing and UV damage repair. These projects mainly employ single particle cryo-EM and electron tomography.